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University Hospitals Dorset NHS Foundation Trust

Antibodies to Nuclear Components

The ANA screen, tested using Indirect Immunofluorescence, has been replaced with the CTD screen (since December 2017). Please contact the laboratory for further information if required.

 

Test

Abbreviation

Clinical Application

Anti-Centromere Abs

ACEN

CREST / Limited cutaneous form of systemic sclerosis

ANA on Hep-2

 

Secondary confirmatory test. Available on request and based on specific clinical details.

Connective Tissue Disease Screen

CTD

Connective tissue disease

Double stranded DNA Abs

DNA

SLE

Extractable nuclear antigens

ENAs

Ro – Sjogren’s, SLELa- Sjogren’s, SLESm – SLE specificRNP- MCTD, SLE

 

Jo-1 – Polymyositis

 

Scl-70 – Scleroderma

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